Hyun Keol Kim, Andreas H. Hielscher, “A diffusion-transport hybrid reconstruction method for accelerating optical tomography”, Journal of Innovative Optical Health Sciences, Vol. 3, No. 4, pp 1–13 (2010) (PDF file).

Hyun Keol Kim, Jong Hwan Lee, Andreas H. Hielscher, “PDE-constrained Fluorescence Tomography with the Frequency-Domain Equation of Radiative Transfer”, IEEE Journal of Selected Topics in Quantum Electronics (Lasers in Medicine and Biology), Issue 99, 10.1109/JSTQE.2009.2038112 (2010)(PDE file).

Ludguier D. Montejo, Alexander D. Klose, Andreas H. Hielscher, "Implementation of the equation of radiative transfer on block-structured grids for modeling light propagation in tissue," Biomedical Optics Express, Vol. 1, Issue 3, pp. 861-878 (2010). (doi:10.1364/BOE.1.000861) (PDF file).

Hyun Keol Kim, Molly L. Flexman, Darrell J. Yamashiro, Jessica J. Kendel, Andreas H. Hielscher, "PDE-constrained multispectral imaging of tissue chromophores with the equation of radiative transfer," Biomedical Optics Express, Vol. 1, Issue 3, pp. 812-824 (2010). (doi:10.1364/BOE.1.000812) (PDF file).

X. Gu, K. Ren, J. Masciotti, A.H. Hielscher, “Parametric image reconstruction using the discrete cosine transform for optical tomography,” J. Biomed. Opt., Vol. 14, 064003 (2009). (doi:10.1117/1.3259360) (PDF file)

Hyun Keol Kim, A.H. Hielscher, “A PDE-constrained SQP algorithm for optical tomography based on the frequency-domain equation of radiative transfer,” Inverse Problems 25,015010 (20pp), (2009). (PDF file)

C.D. Klose, A.D. Klose, U. Netz, J, Beuthan, and A.H. Hielscher, “Multi-parameter classifications of optical tomographic images," Journal of Biomedical Optics 13(05), 050503, (2008). (PDF file)

Hyun Keol Kim, U.J. Netz, J. Beuthan, A.H. Hielscher, "Optimal source-modulation frequencies for transport-theory-based optical tomography of small-tissue volumes," Optics Express, Vol. 16 Issue 22, pp.18082-18101 (2008). (PDF file)

A.D. Klose, A.H. Hielscher, “Diffuse Optical Tomography with the Equation of Radiative Transfer,” International Journal for Numerical Methods in Heat and Fluid Flow 18(3/4), pp. 443-464 (2008).

J.M. Masciotti, J.L. Lasker, A.H. Hielscher, “Digital Lock-in Detection for Discriminating Multiple Modulation Frequencies with High Accuracy and Computational Efficiency,” IEEE Transactions on Instrumentation and Measurement 57(1), pp. 182-189 (2008). (PDF file)

U.J. Netz, J. Beuthan, A.H. Hielscher, “Multipixel System for Gigahertz Frequency-Domain Optical Imaging of Finger Joints,” Review of Scientific Instruments 79(8) 034301 (2008). (PDF file)

J.M. Lasker, J. Masciotti, M. Schoenecker, C. Schmitz, A.H. Hielscher, ”Digital-Signal-Processor-Based Dynamic Optical Tomography Imaging System,” Review of Scientific Instruments 78(8) 083706 (2007). (PDF file)

J.M. Lasker, Christopher J. Fong, Daniel T. Ginat, E. Dwyer, A.H. Hielscher, “Dynamic Optical Imaging of Vascular and Metabolic Reactivity in Rheumatoid Joints,” Journal of Biomedical Optics 12(5), 052001 (September/October 2007). (PDF file)

K. Ren, G. Bal, A.H. Hielscher, “Transport- and diffusion-based optical tomography in small domains: A comparative study,” Applied Optics 46(27) pp. 6669-6679 (2007). (PDF file)

X. Gu, K. Ren, A.H. Hielscher, “Frequency-domain sensitivity analysis for small imaging domains using the equation of radiative transfer,” Applied Optics 46 (10), pp. 1624-1632 (2007). (PDF file)

U.J. Netz, A.H. Hielscher. A.K. Scheel. J. Beuthan, “Experimental results for propagation of diffuse photon-density waves up to 1 Ghz in a tissue-like medium containing an absorbing edge,” Laser Physics 16, pp. 765-773 (2006).

K. Ren, G. Abdoulaev, G. Bal, A.H. Hielscher, "Frequency-domain optical tomography based on the equation of radiative transfer,” SIAM Journal on Scientific Computing 28(4), pp. 1463-1489 (2006). (PDF file)

G. Abdoulaev, K. Ren, A.H. Hielscher, "Optical tomography as a PDE constrained optimization problem,”Inverse Problems 21, pp. 1507–1530 (2005). (PDF file)

A.H, Hielscher, “Optical tomographic imaging of small animals,” Current Opinion in Biotechnology 16(1), pp. 79-88 (2005). (PDF file)

A.K. Scheel, M. Backhaus, A.D. Klose, B. Moa-Anderson, U. Netz, K. G. Hermann, J. Beuthan, G.A. Müller, G.R. Burmester, A.H. Hielscher, "First clinical evaluation of sagittal laser optical tomography for detection of synovitis in arthritic finger joints," Annals of the Rheumatic Diseases 64, pp. 239-245 (2005). (PDF file)

A.D. Klose, V. Ntziachristos, A.H. Hielscher, "The inverse source problem based on the radiative transfer equation in molecular optical imaging," J. of Computational Physics 202, pp. 323-345 (2005). (PDF file)

A.H. Hielscher, A. Klose, A. Scheel, B. Moa-Anderson, M. Backhaus, U. Netz, J. Beuthan, "Sagittal Laser Optical Tomography for Imaging of Rheumatoid Finger Joints," Physics in Medicine and Biology 49(7), pp. 1147 - 1163 (2004). (PDF file)

A.Y. Bluestone, M. Stewart, B. Lei, I.S. Kass, J. Lasker, G.S. Abdoulaev, A.H. Hielscher, "Three-dimensional optical tomographic brain imaging in small animals, Part I: Hypercapnia," Journal of Biomedical Optics 9(5), pp. 1046-1062 (2004). (PDF file)

A.Y. Bluestone, M. Stewart, J. Lasker, G.S. Abdoulaev, A.H. Hielscher, "Three-dimensional optical tomographic brain imaging in small animals, Part II: Unilateral Carotid Occlusion," Journal of Biomedical Optics 9(5), pp. 1063-1073 (2004). (PDF file)

K. Ren, G. Abdoulaev, G. Bal, A.H. Hielscher, "Algorithm for solving the equation of radiative transfer in the frequency domain," Optics Letters 29(6), pp. 578-580 (2004). (PDF file)

A.H. Hielscher and S. Bartel, "Parallel Programming of gradient-based iterative image reconstruction schemes for optical tomography," Computer Methods and Programs in Biomedicine 73(2), pp 101-113 (2004). (PDF file)

A.K. Scheel, U.J. Netz, K.-G.A. Hermann, A.H. Hielscher, A.D. Klose, Volker Tresp, Anton Schwaighofer, G.A. Müller, G.-R. Burmester, M. Backhaus, "Laser imaging techniques for follow-up analysis of joint inflammation in patients with rheumatoid arthritis," Medical Laser Applications 18, pp. 198-205 (2003). (invited).

G. Abdoulaev and A.H. Hielscher, "Three-dimensional optical tomography with the equation of radiative transfer," Journal of Electronic Imaging 12(4), pp. 594-60 (2003). (PDF file)

A.D. Klose, A.H. Hielscher, "Fluorescence tomography with the equation of radiative transfer for molecular imaging," Optics Letters 28(12), pp. 1019-1021 (2003). (PDF file)

A.D. Klose, A.H. Hielscher, "Quasi-Newton methods in optical tomographic imaging," Inverse Problems 19, pp. 387-409 (2003). (PDF file) [Click on scarf to the right!]

A.H. Hielscher, A.Y. Bluestone, G.S.Abdoulaev, A.D. Klose, J. Lasker, M. Stewart, U. Netz, J. Beuthan, "Near-infrared diffuse optical tomography," Disease Markers 18(5-6), pp. 313-337 (2002). (invited) (PDF file)

J. Beuthan, U. Netz, O. Minet, A.D. Klose, A.H. Hielscher, A. Scheel, J. Henniger, G. Müller, "Light scattering study of rheumatoid arthritis," Quantum Electronics 32(11), pp. 945-952 (2002).

C.H. Schmitz, M. Löcker, J.M. Lasker, A.H. Hielscher, R.L. Barbour, "Instrumentation for fast functional optical tomography," Review of Scientific Instrumentation 73(2), pp. 429-439 (2002). (PDF file)

A.D. Klose, U. Netz, J. Beuthan, A.H. Hielscher, "Optical tomography using the time-independent equation of radiative transfer. Part 1: Forward model," Journal of Quantitative Spectroscopy and Radiative Transfer, Vol 72/5, pp 691-713 (2002). (PDF file)

A.D. Klose, A.H. Hielscher, "Optical tomography using the time-independent equation of radiative transfer. Part 2: Inverse model," Journal of Quantitative Spectroscopy and Radiative Transfer, Vol 72/5, pp 715-732 (2002). (PDF file)

J. Beuthan, H.J. Cappius, A.H. Hielscher, M. Hopf, A.D. Klose, U. Netz, " Initial investigations of the applications of linear signal transfer theory to tissue optics, Biomedizinische Technik 46(11), pp. 298-303 (2001).

U. Netz, J. Beuthan, H.J. Capius, H.C. Koch, A.D. Klose, A.H. Hielscher, "Imaging of rheumatoid arthritis in finger joints by sagittal optical tomography, Medical Laser Application 16, pp. 306-310 (2001).

A.Y. Bluestone, G. Abdoulaev, C. Schmitz, R.L. Barbour, A.H. Hielscher, "Three-dimensional optical-tomography of hemodynamics in the human head", Optics Express 9(6), pp. 272-286 (2001). (http://www.opticsexpress.org/abstract.cfm?URI=OPEX-9-6-272)

V. Ntziachristos, A.H. Hielscher, A.G. Yodh, B. Chance, "Diffuse optical tomography of highly heterogeneous media," IEEE Transactions on Medical Imaging 20(6), pp. 470-478 (2001). (PDF file)

A.H. Hielscher and S. Bartel, "Use of penalty terms in gradient-based iterative reconstruction schemes for optical tomography," Journal of Biomedical Optics 6(2), pp. 183-192 (2001). (PDF file)

A.H. Hielscher, A.D. Klose, J. Beuthan, "Evolution strategies for optical tomographic characterization of homogeneous media," Optics Express 7(13), pp. 507-518, 2000. (INVITED) (http://www.opticsexpress.org/abstract.cfm?URI=OPEX-7-13-507).

N. Ramanujam, G. Vishnoi, A.H. Hielscher, M. Rode, I. Forouzan, and B. Chance, "Photon migration through the fetal head in utero using continuous wave, near infrared spectroscopy: Clinical and experimental model studies," Journal of Biomedical Optics 5, pp. 173-184 (2000). (PDF file)

G. Vishnoi, A.H. Hielscher, N. Ramanujam, and B.Chance, "Photon migration through fetal head in utero using continuous wave, near infrared spectroscopy: Development and evaluation of experimental and numerical models," Journal of Biomedical Optics 5, pp. 163-172 (2000). (PDF file)

S. Bartel and A.H. Hielscher, "Monte Carlo simulations of the diffuse backscattering Mueller matrix for highly scattering media," Applied Optics 39, pp. 1580 - 1588 (2000). (PDF file)

A.D. Klose and A.H. Hielscher, "Iterative reconstruction scheme for optical tomography based on the equation of radiative transfer," Medical Physics 26(8), pp. 1698-1707 (1999). (PDF file)

A.H. Hielscher, A.D. Klose, K.M. Hanson, "Gradient-based iterative image reconstruction scheme for time-resolved optical tomography," IEEE Transactions on Medical Imaging 18, pp. 262-271 (1999). (PDF file)

J.R. Mourant, A.H. Hielscher, A.A. Eick, D. Shen, T.M. Johnson, J.P. Freyer, "Evidence for intrinsic differences in light-scattering properties of tumorigenic and nontumorigenic cells," Cancer 84, pp. 366-374 (1998). (PDF file)

A.H. Hielscher, R.E. Alcouffe, R.L. Barbour, "Comparison of finite-difference transport and diffusion calculations for photon migration in homogeneous and heterogeneous tissues," Physics in Medicine and Biology 43, pp. 1285-1302 (1998). (PDF file)

J.R. Mourant, A.H. Hielscher, J.P. Freyer, A.A. Eick, T.M. Johnson, "Mechanisms of light scattering from biological cells relevant to noninvasive optical tissue diagnostic," Applied Optics 37, pp. 3586 - 3593 (1998). (PDF file)

A.H. Hielscher, A.A. Eick, J.R. Mourant, D. Shen, J.P. Freyer, I.J. Bigio, "Diffuse backscattering Mueller matrices for highly scattering media,"Optics Express 1, pp. 441-454 (1997). (http://www.opticsexpress.org/abstract.cfm?URI=OPEX-1-13-441)

A.H. Hielscher, J.R. Mourant, I.J. Bigio, "Influence of particle size and concentration on the diffuse backscattering of polarized light from tissue phantoms and biological cell suspensions," Applied Optics 36, pp. 125-135 (1997).

J.R. Mourant, James Boyer, A.H. Hielscher, I.J. Bigio, "Influence of the scattering phase function on light transport measurements in turbid media performed with small source-detector separations," Optics Letters 21, pp. 546-548 (1996).

A.H. Hielscher, H. Liu, B. Chance, F.K. Tittel, S.L. Jacques, "Time-resolved photon emission from layered turbid media," Applied Optics 35, pp. 719-728 (1996).

A.H. Hielscher, L.Wang , F.K. Tittel, S.L. Jacques, "Influence of boundary conditions on the accuracy of diffusion theory in time-resolved reflectance spectroscopy of biological tissues," Physics in Medicine and Biology 40, pp. 1957-1975 (1995).

H. Liu, A.H. Hielscher, S.L. Jacques, F.K. Tittel, B. Chance, "Influence of blood vessels on the measurement of hemoglobin oxygenation as determined by time-resolved reflectance spectroscopy," Medical Physics 22, pp. 1209-1217 (1995).

A. H. Hielscher, C.E. Miller, D.C. Bayard, K.P. Smolka, R.F. Curl, F.K. Tittel, "Optimization of a mid-infrared high resolution difference frequency laser spectrometer," J. Optical Society of America B 9, pp. 1962-1967 (1992).

P. Canarelli, Z. Benko, A.H. Hielscher, R.F. Curl, F.K. Tittel, "Measurement of nonlinear coefficient and phase matching characteristics of AgGaS2," IEEE Quantum Electronics 28, pp. 52-55 (1992).